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The genome shows its sensitive side

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New methods for measuring the sensitivity of chromatin to DNase digestion and Tn5 transposition help us map and interpret the genome's regulatory sequences.

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Figure 1: Mapping regulatory regions with paired-end DNase-seq or ATAC-seq.

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Authors and Affiliations

  1. Anil Raj and Graham McVicker are in the Department of Genetics, Stanford University, Stanford, California, USA,

    Anil Raj & Graham McVicker

  2. Graham McVicker is in the Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.,

    Graham McVicker

Authors
  1. Anil Raj
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  2. Graham McVicker
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Correspondence to Graham McVicker.

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The authors declare no competing financial interests.

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Raj, A., McVicker, G. The genome shows its sensitive side. Nat Methods 11, 39–40 (2014). https://doi.org/10.1038/nmeth.2770

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