Classification of proteins by ligand binding similarity offers an alternative approach to evolutionary methods for organizing and understanding biology, allowing new insights into protein function and physiological signal transduction.
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van Westen, G., Overington, J. A ligand's-eye view of protein similarity. Nat Methods 10, 116–117 (2013). https://doi.org/10.1038/nmeth.2339
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DOI: https://doi.org/10.1038/nmeth.2339
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