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Six steps closer to FRET-driven structural biology

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A new toolbox for structural biology that combines single-molecule fluorescence and molecular modeling is used to generate high-precision structures of protein complexes.

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Figure 1: A workflow combining smFRET and computer modeling can provide accurate biomolecular structures.

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Correspondence to Timothy D Craggs or Achillefs N Kapanidis.

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Craggs, T., Kapanidis, A. Six steps closer to FRET-driven structural biology. Nat Methods 9, 1157–1158 (2012). https://doi.org/10.1038/nmeth.2257

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