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High-speed microbial community profiling

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A precomputed database of lineage-restricted reference genes yields a fast and accurate tool that uses sequence similarity alone to compute clade abundances from shotgun metagenomic data sets.

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Figure 1: MetaPhlAn simplifies assignment of taxonomies to whole-metagenome shotgun sequencing reads.

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Correspondence to Daniel H Haft.

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Haft, D., Tovchigrechko, A. High-speed microbial community profiling. Nat Methods 9, 793–794 (2012). https://doi.org/10.1038/nmeth.2080

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