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Shedding light on the BOLD fMRI response

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Fluorescence recording of neural activity in the magnetic resonance scanner is a new strategy for examining the cellular underpinnings of blood oxygenation level–dependent (BOLD) functional magnetic resonance imaging (fMRI).

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Figure 1: Experimental approach for examining the relationship between single-cell activity and fMRI signals.

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Authors and Affiliations

  1. Serge Charpak is at Institut National de la Santé et de la Recherche Médicale U603, Paris, France; Centre National de la Recherche Scientifique Unité Mixte de Recherche (UMR) 8154, Paris, France; and Laboratory of Neurophysiology and New Microscopies, Université Paris Descartes, Paris, France.,

    Serge Charpak

  2. Centre National de la Recherche Scientifique Unité Mixte de Recherche (UMR) 8154, Paris, France,

    Serge Charpak

  3. Bojana Stefanovic is at Sunnybrook Research Institute, Toronto, Ontario, Canada.,

    Bojana Stefanovic

Authors
  1. Serge Charpak
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  2. Bojana Stefanovic
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Correspondence to Serge Charpak.

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The authors declare no competing financial interests.

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Charpak, S., Stefanovic, B. Shedding light on the BOLD fMRI response. Nat Methods 9, 547–549 (2012). https://doi.org/10.1038/nmeth.2039

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