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Neighboring-gene effect: a genetic uncertainty principle

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Deletion of a genomic locus may affect the function of neighboring loci, creating genetic uncertainty. Researchers now present a computational algorithm for identifying such neighboring-gene effects and improving the quality of functional annotations.

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Figure 1: Detecting possible NGEs.

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Authors and Affiliations

  1. Anastasia Baryshnikova and Brenda Andrews are at The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.,

    Anastasia Baryshnikova & Brenda Andrews

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  1. Anastasia Baryshnikova
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  2. Brenda Andrews
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Correspondence to Brenda Andrews.

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The authors declare no competing financial interests.

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Baryshnikova, A., Andrews, B. Neighboring-gene effect: a genetic uncertainty principle. Nat Methods 9, 341–343 (2012). https://doi.org/10.1038/nmeth.1936

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