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Microbiology

Prokaryotic RNAi

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Rationally designed RNAs that work with the bacterial immune response allow targeted gene silencing in prokaryotes.

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References

  1. Hale, C.R. et al. Essential features and rational design of CRISPR RNAs that function with the Cas RAMP module complex to cleave RNA. Mol. Cell 45, 292–302 (2012).

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  1. Nicole Rusk
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Rusk, N. Prokaryotic RNAi. Nat Methods 9, 220–221 (2012). https://doi.org/10.1038/nmeth.1916

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