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Making sense out of nonsense to visualize editing in the fly nervous system

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In vivo methods to capture processing events such as RNA editing in specific cell types are sparse. Researchers have now developed a method to visualize adenosine-to-inosine editing activity in individual fruit fly neurons using a reverse-engineered fluorescent reporter.

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Figure 1: Outline of the RNA editing activity reporter.

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Correspondence to Marie Öhman.

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The authors declare no competing financial interests.

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Daniel, C., Öhman, M. Making sense out of nonsense to visualize editing in the fly nervous system. Nat Methods 9, 141–143 (2012). https://doi.org/10.1038/nmeth.1860

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