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Disease models

Method in the madness of fibrosis

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Blocking the growth of new blood vessels has been shown to alter fibrosis in livers in a disease stage-specific manner. In vitro models of fibrosis were developed to understand this process, highlighting the role of environmental mechanics.

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Figure 1: Biomimetic in vitro models of liver fibrosis.

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Authors and Affiliations

  1. the Department of Surgery at Stanford University, 94305-5148, California, USA

    Geoffrey C. Gurtner & Jagannath Padmanabhan

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  1. Geoffrey C. Gurtner
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  2. Jagannath Padmanabhan
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Correspondence to Geoffrey C. Gurtner.

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Gurtner, G., Padmanabhan, J. Method in the madness of fibrosis. Nature Mater 16, 1176–1177 (2017). https://doi.org/10.1038/nmat5044

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