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Implanted materials

Larger is stealthier

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Implanted spheres with a diameter larger than 1.5 mm escape fibrotic responses, thereby extending the survival time of the encapsulated therapeutic cells.

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Figure 1: Foreign body response to alginate spheres encapsulating insulin-producing islet cells.

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Authors and Affiliations

  1. Ruud A. Bank is in the Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands,

    Ruud A. Bank

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  1. Ruud A. Bank
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Correspondence to Ruud A. Bank.

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Bank, R. Larger is stealthier. Nature Mater 14, 558–559 (2015). https://doi.org/10.1038/nmat4304

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