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Cell mechanics

Contracting to stiffness

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Atomic force microscopy experiments on individual blood platelets reveal their dynamic contractile response to varied stiffness of the substrate.

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Figure 1: Platelet-based contractile forces within the fibrin plug increase towards the site of vascular damage.

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Authors and Affiliations

  1. Allen Ehrlicher and John H. Hartwig are at the Translational Medicine Division of Brigham and Women's Hospital, and Harvard Medical School, Karp 6, 1 Blackfan Circle, Boston, Massachusetts 02115, USA. hartwig@rics.bwh.harvard.edu,

    Allen Ehrlicher & John H. Hartwig

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  1. Allen Ehrlicher
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  2. John H. Hartwig
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Ehrlicher, A., Hartwig, J. Contracting to stiffness. Nature Mater 10, 12–13 (2011). https://doi.org/10.1038/nmat2928

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