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Cancer therapy

A twist on tumour targeting

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The concept of using magnetic micro- and nanoparticles for targeting solid tumours with drugs was first proposed over three decades ago, but has yet to translate into a clinical application. Rethinking the mechanistic approach could circumvent the difficulties that have stood in its way.

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Figure 1: Magnetic spin-vortex discs (shown in green) are coated with antibodies (shown in blue) that bind to membrane receptors expressed by the cancer cells.

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Authors and Affiliations

  1. and in the Department of Materials Science and Engineering, Jon Dobson is at the Institute for Science and Technology in Medicine, Keele University, Thornburrow Drive, Hartshill, Stoke-on-Trent, ST4 7QB, UK, University of Florida, Gainesville, Florida 32611, USA. bea22@keele.ac.uk,

    Jon Dobson

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  1. Jon Dobson
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Dobson, J. A twist on tumour targeting. Nature Mater 9, 95–96 (2010). https://doi.org/10.1038/nmat2604

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