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RIG-ing an antitumor response

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A small interfering RNA has been engineered to silence an oncogene and activate the immune response simultaneously. The approach shrinks tumors in mice (pages 1256–1263).

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Figure 1: A dual-function small RNA.

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Authors and Affiliations

  1. Fabio Petrocca and Judy Lieberman are at the Immune Disease Institute and Department of Pediatrics, Harvard Medical School, 200 Longwood Avenue, Boston, Massachusetts, 02115, USA. lieberman@idi.harvard.edu,

    Fabio Petrocca & Judy Lieberman

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  1. Fabio Petrocca
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  2. Judy Lieberman
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Competing interests

J.L. is on the Scientific Advisory Board of Alnylam Pharmaceuticals and Cequent Pharmaceuticals.

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Petrocca, F., Lieberman, J. RIG-ing an antitumor response. Nat Med 14, 1152–1153 (2008). https://doi.org/10.1038/nm1108-1152

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