The promise of disease-modifying treatments for Alzheimer disease calls for biomarkers that enable early diagnosis. A new discovery shows how to visualize amyloid pathology in living Alzheimer patients.
This is a preview of subscription content, log in via an institution to check access.
References
Masters, C.L. et al. Proc. Natl. Acad. Sci. USA 82, 4245–4249 (1985).
Hardy, J. & Selkoe, D.J. Science 297, 353–356 (2002).
Blennow, K., de Leon, M.J. & Zetterberg, H. Lancet (In the press).
Klunk, W.E. et al. Ann. Neurol. 55, 306–319 (2004).
Klunk, W.E. et al. J. Neurosci. 23, 2086–2092 (2003).
Klunk, W.E., et al. J. Neurosci. 25, 10598–10606 (2005).
Fagan, A.M. et al. Ann. Neurol. 59, 512–519 (2006).
Petersen, R.C. J. Intern. Med. 256, 183–194 (2004).
Duff, K. & Suleman, F. Brief. Funct. Genomic. Proteomic. 3, 47–59 (2004).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Blennow, K., Zetterberg, H. Pinpointing plaques with PIB. Nat Med 12, 753–754 (2006). https://doi.org/10.1038/nm0706-753
Issue Date:
DOI: https://doi.org/10.1038/nm0706-753
- Springer Nature America, Inc.
This article is cited by
-
Neuroinflammation and neurohormesis in the pathogenesis of Alzheimer’s disease and Alzheimer-linked pathologies: modulation by nutritional mushrooms
Immunity & Ageing (2018)
-
Synthesis and biodistribution of novel dansyl derivative 11C-DSB
Journal of Radioanalytical and Nuclear Chemistry (2018)
-
Monte Carlo feature selection and rule-based models to predict Alzheimer’s disease in mild cognitive impairment
Journal of Neural Transmission (2012)