Skip to main content
Log in

Sudden Cardio Arrest: Oxidative stress irritates the heart

  • Between Bedside and Bench
  • Published:

From Nature Medicine

View current issue Submit your manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: Myocardial stress upsets the balance between antioxidant defense systems and production of ROS.

Kimberly Caesar

References

  1. Chugh, S.S. et al. J. Am. Coll. Cardiol. 44, 1268–1275 (2004).

    Article  Google Scholar 

  2. The Cardiac Arrhythmia Suppression Trial (CAST) Investigators. N. Engl. J. Med. 321, 406–412 (1989).

  3. Xie, L.H., Chen, F., Karagueuzian, H.S. & Weiss, J.N. Circ. Res. 104, 79–86 (2009).

    Article  CAS  Google Scholar 

  4. Erickson, J.R. et al. Cell 133, 462–474 (2008).

    Article  CAS  Google Scholar 

  5. Chen, Q., Vazquez, E.J., Moghaddas, S., Hoppel, C.L. & Lesnefsky, E.J. J. Biol. Chem. 278, 36027–36031 (2003).

    Article  CAS  Google Scholar 

  6. O'Rourke, B., Cortassa, S. & Aon, M.A. Physiology (Bethesda) 20, 303–315 (2005).

    CAS  Google Scholar 

  7. Marx, S.O. et al. Science 295, 496–499 (2002).

    Article  CAS  Google Scholar 

  8. Marx, S.O. et al. Cell 101, 365–376 (2000).

    Article  CAS  Google Scholar 

  9. Zhang, R. et al. Nat. Med. 11, 409–417 (2005).

    Article  CAS  Google Scholar 

  10. Lyle, A.N. & Griendling, K.K. Physiology (Bethesda) 21, 269–280 (2006).

    CAS  Google Scholar 

  11. Yang, Y. et al. Am. J. Physiol. Heart Circ. Physiol. 291, H3065–H3075 (2006).

    Article  CAS  Google Scholar 

  12. Münzel, T. & Gori, T. J. Am. Coll. Cardiol. 54, 1491–1499 (2009).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Gordon F Tomaselli.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Tomaselli, G., Barth, A. Sudden Cardio Arrest: Oxidative stress irritates the heart. Nat Med 16, 648–649 (2010). https://doi.org/10.1038/nm0610-648

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nm0610-648

  • Springer Nature America, Inc.

This article is cited by

Navigation