A variety of immune cell types contribute to disease in individuals with multiple sclerosis, an autoimmune condition of the central nervous system. Thomas Prod'homme and Scott Zamvil comment on the 'Bench to Bedside' approach, examining how recent basic research implicates the antigen-presenting cell in this disease. In our 'Bedside to Bench' column, Hans Link explores how recent clinical trials may bolster a mechanistic role for the B cell.
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Link, H. Betting on B cells in multiple sclerosis. Nat Med 14, 615–616 (2008). https://doi.org/10.1038/nm0608-615
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DOI: https://doi.org/10.1038/nm0608-615
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