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Bone loss goes beyond estrogen

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The central position of estrogen in the physiological and pharmacological control of bone resorption is now challenged by evidence from mouse genetics of estrogen-independent control by pituitary FSH.

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Figure 1: The potential effects of FSH on the skeleton in vivo, either directly upon bone or indirectly.

Katie Ris

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Authors and Affiliations

  1. St. Vincent's Institute of Medical Research, Victoria, 3065, Fitzroy, Australia

    T John Martin

  2. Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, 72205, Arkansas, USA

    Dana Gaddy

Authors
  1. T John Martin
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  2. Dana Gaddy
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Martin, T., Gaddy, D. Bone loss goes beyond estrogen. Nat Med 12, 612–613 (2006). https://doi.org/10.1038/nm0606-612

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