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Less stress, longer life

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The theory that oxidative stress limits lifespan and causes age-related disease rests on experiments in invertebrates and correlative evidence from studies in mammals. This theory now gains a strong experimental basis in mammals.

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Figure 1: Powering up lifespan.

Katie Ris

References

  1. Schriner, S.E. et al. Science, Published online 5 May 2005 (10.1126/science.1106653).

  2. Wang, Y. et al. Proc. Natl. Acad. Sci. USA 98, 4022–4027 (2001).

    Article  CAS  Google Scholar 

  3. Zhang, J. et al. Proc. Natl. Acad. Sci. USA 100, 1116–1121 (2003).

    Article  CAS  Google Scholar 

  4. Wang, J., Xiong, S., Xie, C., Markesbery, W.R. & Lovell, M.A. J. Neurochem. 93, 953–962 (2005).

    Article  CAS  Google Scholar 

  5. Mecocci, P. et al. Ann. Neurol. 34, 609–616 (1993).

    Article  CAS  Google Scholar 

  6. Lin, M.T., Simon, D.K., Ahn, C.H., Kim, L.M. & Beal, M.F. Hum. Mol. Genet. 11, 133–145 (2002).

    Article  CAS  Google Scholar 

  7. Trifunovic, A. et al. Nature 429, 417–423 (2004).

    Article  CAS  Google Scholar 

  8. Lu, T. et al. Nature 429, 883–891 (2004).

    Article  CAS  Google Scholar 

  9. Ruan, H. et al. Proc. Natl. Acad. Sci. USA 99, 2748–2753 (2002).

    Article  CAS  Google Scholar 

  10. Moskovitz, J. et al. Proc. Natl. Acad. Sci. USA 98, 12920–12925 (2001).

    Article  CAS  Google Scholar 

  11. Mitsui, A. et al. Antioxid. Redox Signal. 4, 693–696 (2002).

    Article  CAS  Google Scholar 

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Beal, M. Less stress, longer life. Nat Med 11, 598–599 (2005). https://doi.org/10.1038/nm0605-598

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