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Blood pressure control: salt gets under your skin

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After an increase in dietary salt, the excess sodium is stored under the skin—stimulating lymphatic growth through the activity of macrophages (pages 545–552). The findings should recast thinking about how blood pressure is regulated.

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Figure 1: Increased subcutaneous Na+ modulates lymphangiogenesis and blood pressure.

Kim Caesar

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Authors and Affiliations

  1. Paul J. Marvar and David G. Harrison are in the Department of Medicine Division of Cardiology, and Frank J. Gordon is in the Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia, USA.,

    Paul J Marvar, Frank J Gordon & David G Harrison

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  1. Paul J Marvar
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  2. Frank J Gordon
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  3. David G Harrison
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Correspondence to David G Harrison.

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Marvar, P., Gordon, F. & Harrison, D. Blood pressure control: salt gets under your skin. Nat Med 15, 487–488 (2009). https://doi.org/10.1038/nm0509-487

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