Skip to main content

Advertisement

SpringerLink
Log in

Closing in on human immunodeficiency virus–1

  • News & Views
  • Published:

From Nature Medicine

View current issue Submit your manuscript

Antiretroviral therapy back on track with HIV-1 protease inhibitors.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Aboulker, J.P. & Swart, A.M. Preliminary analysis of the Concorde trial. Lancet 329, 889–890 (1993).

    Article  Google Scholar 

  2. Fischl, M.A. et al. Combination and monotherapy with zidovudine and zalcitabine in patients with advanced HIV disease. Ann. Intern. Med. 122, 24–32 (1995).

    Article  CAS  Google Scholar 

  3. Delfraissy, J.F. et al. Abstracts of the IXth Int. Conference on AIDS, Berlin, Germany, p.69 (1993).

  4. Danner, S.A. et al. Abstracts of the IXth Int. Conference on AIDS, Berlin, Germany, p.69 (1993).

  5. Chow, Y.K. et al. Use of evolutionary limitations of HIV-1 multidrug resistance to optimize therapy. Nature 361, 650–654 (1993).

    Article  CAS  Google Scholar 

  6. Emini, E.A. et al. HIV and multidrug resistance. Nature 364, 679 (1993).

    Article  CAS  Google Scholar 

  7. Larder, B.A., Kellam, P. & Kemp, S.D. Convergent combination therapy can select viable multidrug-resistant HIV-1 in vitro. Nature 365, 451–453 (1993).

    Article  CAS  Google Scholar 

  8. Mellors, J.W. Abstracts of the 3rd Conference on Retroviruses and Opportunistic Infections, Washington, DC, 175 (1996).

  9. Hammer, S.M., Katzenstein, D.A., Hughes, M.D., Hirsch, M.S. & Merigan, T.C. Abstracts 3rd Conf. Retroviruses and Opportunistic Infections, Washington, DC, 175 (1996).

  10. Cameron, B. et al. Abstracts 3rd Conf. Retrovir. & Opportun. Infect., Washington, DC, p.162 (1996).

  11. Freimuth, W.W. et al. Abstracts 3rd Conf. Retrovir. & Opportun. Infect., Washington, DC, p.162 (1996).

  12. Gulick, R. et al. Abstracts 3rd Conf. Retrovir. & Opportun. Infect., Washington, DC, p.162 (1996).

  13. Mathez, D. et al. Abstracts 3rd Conf. Retrovir. & Opportun. Infect., Washington, DC, p. 106 (1996).

    Google Scholar 

  14. Coffin, J.M. HIV population dynamics in vivo: Implications for genetic variation, pathogenesis, and therapy. Science 267, 483–489 (1995).

    Article  CAS  Google Scholar 

  15. Wei, X. et al. Viral dynamics in human immunodeficiency virus type 1 infection. Nature 373, 117–122 (1995).

    Article  CAS  Google Scholar 

  16. Ho, D.D. et al. Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature 373, 123–126 (1995).

    Article  CAS  Google Scholar 

  17. Perelson, A.S., Neumann, A.U., Markowitz, M., Leonard, J.M. & Ho, D.D. Abstracts 3rd Conf. Retrovir. & Opportun. Infect., Washington, DC, p.174 (1996).

  18. Mellors, J. et al. Abstracts 35th Intersci. Conf. on Antimicrobial Agents and Chemotherapy, San Francisco, California, 235 (1995).

  19. Condra, J.H. et al. In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors. Nature 374, 569–571 (1995).

    Article  CAS  Google Scholar 

  20. Steigbigel, R.T. et al Abstracts 3rd Conf. Retrovir. & Opportun. Infect., Washington, DC, p.80 (1996).

  21. Danner, S.A. et al. A short-term study of the safety, pharmacokinetics, and efficacy of ritonavir, an inhibitor of HIV-1 protease. N. Engl. J. Med. 333, 1528–1533 (1995).

    Article  CAS  Google Scholar 

  22. Markowitz, M. et al. A preliminary study of ritonavir, an inhibitor of HIV-1 protease, to treat HIV-1 infection. N. Engl. J. Med. 333, 1534–1539 (1995).

    Article  CAS  Google Scholar 

  23. Schapiro, J.M., Winters, M.A., Kozal, M.J. & Merigan, T.C. Abstracts 35th Intersci. Conf. Antimicrobial Agents and Chemotherapy, San Francisco, California, p.S8 (1995).

Download references

Author information

Authors and Affiliations

  1. Department of Veterans Affairs Medical Center, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, 15213, USA

    John W. Mellors

Authors
  1. John W. Mellors
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Mellors, J. Closing in on human immunodeficiency virus–1. Nat Med 2, 274–275 (1996). https://doi.org/10.1038/nm0396-274

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nm0396-274

  • Springer Nature America, Inc.

This article is cited by

Search

Navigation