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eLiXiRs for restraining inflammation

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New data implicate the LXRs, a class of nuclear hormone receptors, in reducing inflammation. When activated, these receptors ease inflammation in three mouse models. The results are relevant to atherosclerosis, Alzheimer disease, sepsis and other inflammatory disorders (pages 213–219).

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Figure 1: LXRs regulate inflammation and lipid metabolism.

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Correspondence to Mason W. Freeman.

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Freeman, M., Moore, K. eLiXiRs for restraining inflammation. Nat Med 9, 168–169 (2003). https://doi.org/10.1038/nm0203-168

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