A cancer genetics dogma states that hematologic malignancies arise as a result of defined chromosomal translocations, whereas mutations underlie epithelial solid tumors. This rule is now broken in an analysis of chromosomal translocations in prostate cancer.
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Shaffer, D., Pandolfi, P. Breaking the rules of cancer. Nat Med 12, 14–15 (2006). https://doi.org/10.1038/nm0106-14
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DOI: https://doi.org/10.1038/nm0106-14
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