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Setting the cytokine trap for autoimmunity

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Agents that block the action of specific cytokines have changed the lives of many patients with rheumatoid arthritis and other autoimmune disorders. But frequent self-injections or injections by a physician during a clinic visit are required. Now a new class of anti-cytokine that may bypass such problems appears on the horizon (pages 47–52).

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Figure 1: Blocking IL-1 activity.
Figure 2: Cytokine trap treats inflammation in arthritic mice.

Courtesy of E. Koehler-Stec, T. Sterlacci and S. Staton

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Dinarello, C. Setting the cytokine trap for autoimmunity. Nat Med 9, 20–22 (2003). https://doi.org/10.1038/nm0103-20

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