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A human cellular model of amyotrophic lateral sclerosis

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Stem cell–derived human motor neurons were used to investigate the cellular mechanisms underlying C9ORF72-related amyotrophic lateral sclerosis.

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Figure 1: Intronic repeats in C9ORF72 cause loss of human motor neurons.

Marina Corral Spence/Springer Nature

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Authors and Affiliations

  1. the Program in Stem Cell Biology and Regenerative Medicine and the Department of Psychiatry and Behavioral Sciences at Stanford University, Stanford, California, USA

    Rebecca M Marton

  2. Department of Psychiatry and Behavioral Sciences at Stanford University, Stanford, California, USA

    Sergiu P Paşca

Authors
  1. Rebecca M Marton
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  2. Sergiu P Paşca
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Correspondence to Sergiu P Paşca.

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The authors declare no competing financial interests.

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Marton, R., Paşca, S. A human cellular model of amyotrophic lateral sclerosis. Nat Med 24, 256–257 (2018). https://doi.org/10.1038/nm.4509

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