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Increasing the neurological-disease toolbox using iPSC-derived microglia

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A new study presents a protocol to differentiate human induced pluripotent stem cells (iPSCs) into microglia that closely resemble their in vivo counterparts. These cells offer an exciting new tool for learning more about the role of microglia in disease.

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Figure 1: Derivation of microglia from iPSCs.

Katie Vicari/Nature Publishing Group

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Correspondence to Beth Stevens.

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Hammond, T., Stevens, B. Increasing the neurological-disease toolbox using iPSC-derived microglia. Nat Med 22, 1206–1207 (2016). https://doi.org/10.1038/nm.4226

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