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References
Sadanandam, A. et al. Nat. Med. 19, 619–625 (2013).
Del Rio, M. et al. J. Clin. Oncol. 25, 773–780 (2007).
Acknowledgements
This work was supported by grants from the Instituto de Salud Carlos III COMBIOMED (RD07/0067/0014), the Spanish MINECO (BIO2012-40205) and the US National Cancer Institute (R01-CA116554 and R01-CA129963). We thank D. Juan for advice on methodology and helpful discussions.
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R.M.-G., D.R., A.V. and M.H. were responsible for conception and design. P.P.L.-C. coordinated the experimental work. All authors were responsible for interpretation of data. R.M.-G. and D.R. drafted the initial manuscript. All authors critically revised and approved the manuscript for publication.
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Martinez-Garcia, R., Lopez-Casas, P., Rico, D. et al. Colorectal cancer classification based on gene expression is not associated with FOLFIRI response. Nat Med 20, 1230–1231 (2014). https://doi.org/10.1038/nm.3701
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DOI: https://doi.org/10.1038/nm.3701
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