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Initiating type I diabetes: new suspects in the lineup

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Several physiological and pathological events taking place postnatally in or around the pancreatic islets of Langerhans have been implicated in the initiation of type 1 diabetes. A new study highlights the contribution of neutrophils and how they, together with B1a cells and plasmacytoid dendritic cells (pDCs), may start the autoimmune process (pages 65–73).

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Figure 1: Pathological game of Clue in the islets of Langerhans: how nobody is an innocent bystander.

Marina Corral

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Authors and Affiliations

  1. Rémi J. Creusot is at the Columbia Center for Translational Immunology and the Naomi Berrie Diabetes Center, New York, New York, USA.,

    Rémi J Creusot

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  1. Rémi J Creusot
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Correspondence to Rémi J Creusot.

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Creusot, R. Initiating type I diabetes: new suspects in the lineup. Nat Med 19, 18–20 (2013). https://doi.org/10.1038/nm.3044

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