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On the road from classical to modern molecular biology

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Figure 1: Photos of me and my colleagues taken circa 1976–1978.
Figure 2: Schematic illustrating the synthesis and cloning of double-stranded cDNA from purified rabbit β-globin mRNA using the sequential activities of reverse transcriptase and DNA polymerase I.
Figure 3: Schematic illustrating our strategy for the construction of a genomic DNA library.

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Authors and Affiliations

  1. Tom Maniatis is in the Department of Biochemistry & Biophysics, Columbia University, New York, New York, USA.,

    Tom Maniatis

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  1. Tom Maniatis
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Correspondence to Tom Maniatis.

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Competing interests

T.M. receives royalty payments on the sale of bortezomid as a scientific founder of ProScript and as an inventor on US patent number 6660268, entitled “Proteasome regulation of NF-κB activity.”

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Maniatis, T. On the road from classical to modern molecular biology. Nat Med 18, 1499–1502 (2012). https://doi.org/10.1038/nm.2931

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