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Untuning the tumor metabolic machine: HIF-α: pro- and antitumorigenic?

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Figure 1: A model for how 2HG promotes glioma transformation.

Kaite Vicari

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Authors and Affiliations

  1. Regina M Young and M Celeste Simon are at the Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania, USA.,

    Regina M Young & M Celeste Simon

  2. Regina M Young is also in the Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.,

    Regina M Young

  3. M Celeste Simon is also at the Howard Hughes Medical Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.,

    M Celeste Simon

Authors
  1. Regina M Young
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  2. M Celeste Simon
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Correspondence to M Celeste Simon.

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The authors declare no competing financial interests.

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Young, R., Simon, M. Untuning the tumor metabolic machine: HIF-α: pro- and antitumorigenic?. Nat Med 18, 1024–1025 (2012). https://doi.org/10.1038/nm.2865

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