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To survive radiation injury, remember your aPCs

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Acute exposure to ionizing radiation can cause lethality via severe damage to the hematopoietic system. A new study shows that infusion of the anticoagulants thrombomodulin or activated protein C reduces radiation toxicities and improves survival (pages 1123–1129).

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Figure 1: Thrombomodulin and aPC can mitigate radiation-induced toxicity.

Katie Vicari

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Authors and Affiliations

  1. John P. Chute is in the Division of Cellular Therapy, Duke University Medical Center, Durham, North Carolina, USA.,

    John P Chute

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  1. John P Chute
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Correspondence to John P Chute.

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Chute, J. To survive radiation injury, remember your aPCs. Nat Med 18, 1013–1014 (2012). https://doi.org/10.1038/nm.2859

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