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Regulatory ripples

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Regulatory T cells come in many different forms depending on their mode of action or developmental origin. Data now show that interleukin 35, an immunomodulatory cytokine secreted by regulatory T cells, and interleukin 10 induce so-called 'iTR35 cells', which may have an important role in the phenomenon of infectious tolerance.

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Figure 1: Regulatory networks.

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Authors and Affiliations

  1. Yasmine Belkaid is with the Mucosal Immunology Unit, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.,

    Yasmine Belkaid

  2. WanJun Chen is with the Mucosal Immunology Unit, National Institutes of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA.,

    WanJun Chen

Authors
  1. Yasmine Belkaid
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  2. WanJun Chen
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Correspondence to Yasmine Belkaid.

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The authors declare no competing financial interests.

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Belkaid, Y., Chen, W. Regulatory ripples. Nat Immunol 11, 1077–1078 (2010). https://doi.org/10.1038/ni1210-1077

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