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MicroRNA-managing the TH-17 inflammatory response

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The differentiation of interleukin 17–producing helper T cells is controlled by a complex network of cytokines, signaling pathways and transcription factors. Regulation by microRNA particles can now be added to this list.

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Figure 1: The microRNA miR-326 encourages TH-17 differentiation.

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Authors and Affiliations

  1. Aaron J. Martin and Stephen D. Miller are in the Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.,

    Aaron J Martin & Stephen D Miller

  2. Liang Zhou is in the Department of Microbiology-Immunology and Department of Pathology and The Interdepartmental Immunobiology Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.,

    Liang Zhou

Authors
  1. Aaron J Martin
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  2. Liang Zhou
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  3. Stephen D Miller
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Correspondence to Stephen D Miller.

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Martin, A., Zhou, L. & Miller, S. MicroRNA-managing the TH-17 inflammatory response. Nat Immunol 10, 1229–1231 (2009). https://doi.org/10.1038/ni1209-1229

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