Induction of the microRNA miR-182 by interleukin 2 in helper T lymphocytes targets the transcription factor Foxo1 and promotes clonal expansion. Targeting this process opens new possibilities for adjuvancy, immunosuppression and anti-inflammatory therapeutics.
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O'Neill, L. Outfoxing Foxo1 with miR-182. Nat Immunol 11, 983–984 (2010). https://doi.org/10.1038/ni1110-983
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DOI: https://doi.org/10.1038/ni1110-983
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