The work of epidemiologists before the isolation of human immunodeficiency virus 25 years ago demonstrates the power of the epidemiological method to gain an understanding of disease pathogenesis.
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Jaffe, H. The early days of the HIV-AIDS epidemic in the USA. Nat Immunol 9, 1201–1203 (2008). https://doi.org/10.1038/ni1108-1201
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DOI: https://doi.org/10.1038/ni1108-1201
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