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Unraveling B cell receptor mechanics

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The B cell antigen receptor complex serves as a 'multipurpose machine'. Two new studies provide mechanistic insights into its activation- and anergy-related functions.

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Figure 1: BCRs in resting and antigen-stimulated cells.

Katie Ris

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Wienands, J. Unraveling B cell receptor mechanics. Nat Immunol 6, 1072–1074 (2005). https://doi.org/10.1038/ni1105-1072

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