The production of type I interferon—the first line of defense against virus infection and critical for innate immunity—in plasmacytoid dendritic cells relies on the mammalian target of rapamycin.
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Costa-Mattioli, M., Sonenberg, N. RAPping production of type I interferon in pDCs through mTOR. Nat Immunol 9, 1097–1099 (2008). https://doi.org/10.1038/ni1008-1097
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DOI: https://doi.org/10.1038/ni1008-1097
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