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A birthday gift for TRADD

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Definitive new data solidify and clarify the function of the adaptor TRADD in tumor necrosis factor receptor 1 signaling and show that in some situations, TRADD is also required for the transmission of Toll-like receptor signals.

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Figure 1: TNFR1-mediated signal transduction with and without TRADD.

Katie Ris-Vicari

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Natoli, G., Austenaa, L. A birthday gift for TRADD. Nat Immunol 9, 1015–1016 (2008). https://doi.org/10.1038/ni0908-1015

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