New findings show that cellular microRNAs 'calibrate' the baseline expression of mRNAs encoding stress-inducible ligands of the activating NKG2D receptor. This regulation serves to protect innocent cells but may be exploited by tumors and viruses to thwart immune attack.
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Katie Ris-Vicari
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Spies, T. Regulation of NKG2D ligands: a purposeful but delicate affair. Nat Immunol 9, 1013–1015 (2008). https://doi.org/10.1038/ni0908-1013
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DOI: https://doi.org/10.1038/ni0908-1013
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