T cell help is not obligatory for B cell Ig class switching. Instead, DC expression of BLyS and APRIL can provide the signals to induce T-independent B cell production of IgG and IgA.
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Macpherson, A., Lamarre, A. BLySsful interactions between DCs and B cells. Nat Immunol 3, 798–800 (2002). https://doi.org/10.1038/ni0902-798
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DOI: https://doi.org/10.1038/ni0902-798
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