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Turning over the Chance card on MS susceptibility

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CD8+ T cells expressing two distinct T cell antigen receptors fail to be tolerized and can induce autoimmunity.

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Figure 1: A model for understanding the role of chance in the pathogenesis of multiple sclerosis.

Katie vicari

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  1. Richard M. Ransohoff is with the Cleveland Clinic Neurosciences and Neurology, Cleveland, Ohio, USA.,

    Richard M Ransohoff

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  1. Richard M Ransohoff
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Correspondence to Richard M Ransohoff.

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Ransohoff, R. Turning over the Chance card on MS susceptibility. Nat Immunol 11, 570–572 (2010). https://doi.org/10.1038/ni0710-570

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