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Hematopoiesis flies high with Ikaros

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Ikaros regulatory proteins are essential for proper lymphoid cell development. Several new functions for Ikaros have been defined by surrogate marker expression in early hematopoietic progenitor populations.

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Figure 1: Working model of early hematopoietic development.

Katie Ris

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Authors and Affiliations

  1. Department of Microbiology, Howard Hughes Medical Institute, Immunology, and Molecular Genetics, David Geffen School of Medicine at UCLA, Los Angeles, 90095, California, USA

    Stephen T Smale

  2. Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, 90095, California, USA

    Kenneth Dorshkind

Authors
  1. Stephen T Smale
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  2. Kenneth Dorshkind
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Smale, S., Dorshkind, K. Hematopoiesis flies high with Ikaros. Nat Immunol 7, 367–369 (2006). https://doi.org/10.1038/ni0406-367

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