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How T cells 'find' the right dendritic cell

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Naive T cells can spend hours 'sampling' dendritic cells before making a stable conjugate with a single dendritic cell. It is the antigen 'dose' that determines how long this process takes.

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Figure 1: A period of T cell motility precedes a period of stable interactions with DCs.

Katie Ris-Vicari

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  1. Andrey S. Shaw is in the Department of Pathology and Immunology, Howard Hughes Medical Institute, Washington University, St. Louis, Missouri 63110, USA. ashaw@wustl.edu,

    Andrey S Shaw

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  1. Andrey S Shaw
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Shaw, A. How T cells 'find' the right dendritic cell. Nat Immunol 9, 229–230 (2008). https://doi.org/10.1038/ni0308-229

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