Skip to main content
SpringerLink
Log in

Thymocyte differentiation: it's time to bend a little

  • News & Views
  • Published:

From Nature Immunology

View current issue Submit your manuscript

The development of new experimental tools is helping to unravel the molecular secrets of cell differentiation. The identification, by gene chip technology, of a HMG box protein called TOX has yielded valuable information about thymocyte differentiation.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: Possible disruption of nucleosomes.

Bob Crimi

References

  1. Wilkinson, B. et al. Nature Immunol. 3, 272–280 (2002).

    Article  CAS  Google Scholar 

  2. Robey, E. & Fowlkes, B. J. Annu. Rev. Immunol. 12, 675–705 (1994).

    Article  CAS  PubMed  Google Scholar 

  3. Godfrey, D. I., Kennedy, J., Suda, T. & Zlotnik, A. J. Immunol. 150, 4244–4252 (1993).

    CAS  PubMed  Google Scholar 

  4. Basson, M. A. & Zamoyska, R. Immunol. Today 21, 509–514 (2000).

    Article  CAS  PubMed  Google Scholar 

  5. Lee, G. R., Fields, P. E. & Flavell, R. A. Immunity 14, 447–459 (2001).

    Article  CAS  PubMed  Google Scholar 

  6. Lopez-Rodriguez, C. et al. Immunity 15, 47–58 (2001).

    Article  CAS  PubMed  Google Scholar 

  7. Hostert, A. et al. Immunity. 9, 497–508 (1998).

    Article  CAS  PubMed  Google Scholar 

  8. Ellmeier, W., Sawada, S. & Littman, D. Annu. Rev. Immunol. 17, 523–554 (1999).

    Article  CAS  PubMed  Google Scholar 

  9. Reya, T., Okamura, R. & Grosschedl, R. Cold Spring Harb. Symp. Quant. Biol. 64, 133–140 (1999).

    Article  CAS  PubMed  Google Scholar 

  10. Staal, F. J et al. Stem Cells 19, 165–179 (2001).

    Article  CAS  PubMed  Google Scholar 

  11. Zhuma, T. et al. EMBO J. 18, 6396–6406 (1999).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Schmedt, C. & Tarakhovsky, A. J. Exp. Med. 193, 815–826 (2001).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Molecular Immunology, National Institute for Medical Research, The Ridgeway, NW7 1AA, London, UK

    Dimitris Kioussis

Authors
  1. Dimitris Kioussis
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kioussis, D. Thymocyte differentiation: it's time to bend a little. Nat Immunol 3, 214–215 (2002). https://doi.org/10.1038/ni0302-214

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/ni0302-214

  • Springer Nature America, Inc.

This article is cited by

Search

Navigation