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Choreography of MAGUKs during T cell activation

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T cell receptor activation requires the membrane-associated guanylate kinase CARMA1. A new study finds that a second such kinase, Dlgh1, is also required specifically for activation of the alternative p38 kinase pathway.

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Figure 1: Activation of p38 in T cells.

Katie Ris

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Authors and Affiliations

  1. Department of Medicine, Immunology Program, University of Vermont, Burlington, 05405, Vermont, USA

    Mercedes Rincón

  2. Howard Hughes Medical Institute and Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, 01605, Massachusetts, USA

    Roger J Davis

Authors
  1. Mercedes Rincón
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  2. Roger J Davis
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The authors declare no competing financial interests.

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Rincón, M., Davis, R. Choreography of MAGUKs during T cell activation. Nat Immunol 8, 126–127 (2007). https://doi.org/10.1038/ni0207-126

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