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ZAPS electrifies RIG-I signaling

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ZAPS, a member of the poly(ADP-ribose) polymerase family, modulates innate antiviral immunity by boosting signaling of the RNA helicase RIG-I.

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Figure 1: Model of the regulation of RIG-I antiviral activity and the innate immune response by ZAPS.

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Authors and Affiliations

  1. Helene Minyi Liu and Michael Gale Jr. are in the Department of Immunology, University of Washington School of Medicine, Seattle, Washington, USA.,

    Helene Minyi Liu & Michael Gale Jr

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  1. Helene Minyi Liu
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  2. Michael Gale Jr
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Correspondence to Michael Gale Jr.

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The authors declare no competing financial interests.

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Liu, H., Gale, M. ZAPS electrifies RIG-I signaling. Nat Immunol 12, 11–12 (2011). https://doi.org/10.1038/ni0111-11

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