The US National Institutes of Health convened a workshop on disease-promoting chronic inflammation to identify the challenges and needs in the development of clinically feasible strategies for monitoring a person's inflammation status before, during and after disease occurrence.
This is a preview of subscription content, log in via an institution to check access.
Debbie Maizels/Springer Nature
References
Ashley, N.T., Weil, Z.M. & Nelson, R. Annu. Rev. Ecol. Evol. Syst. 43, 385–406 (2012).
Goldberg, E.L. & Dixit, V.D. Immunol. Rev. 265, 63–74 (2015).
Wiley, C.D. & Campisi, J. Cell Metab. 23, 1013–1021 (2016).
Dzutsev, A. et al. Annu. Rev. Immunol. 35, 199–228 (2017).
Kannan, S. et al. Sci. Transl. Med. 4, 130ra146 (2012).
Lamont, R.J. & Hajishengallis, G. Trends Mol. Med. 21, 172–183 (2015).
Martins, M.D. et al. J. Dent. Res. 95, 215–222 (2016).
Morrison, L. et al. BMC Cancer 16, 80 (2016).
Varadhan, R. et al. J. Gerontol. A Biol. Sci. Med. Sci. 69, 165–173 (2014).
Roy, N.S., Wei, Y., Kuklinski, E. & Asbell, P.A. Invest. Ophthalmol. Vis. Sci. 58, BIO1–BIO19 (2017).
Tracy, R.P. et al. J. Am. Heart Assoc. 2, e000117 (2013).
Kreisl, W.C. et al. Neurobiol. Aging 44, 53–61 (2016).
Shin, S.H., Kadayakkara, D.K. & Bulte, J.W. Radiology 282, 194–201 (2017).
Wang, L.V. & Yao, J. Nat. Methods 13, 627–638 (2016).
Abram, T.J. et al. Oral Oncol. 60, 103–111 (2016).
Nakagawa, S. et al. Cancer Cell 30, 879–890 (2016).
Zierer, J. et al. Sci. Rep. 6, 37646 (2016).
Newman, A.B. et al. Int. J. Epidemiol. 45, 1135–1145 (2016).
Zhen, Y., Chu, C., Zhou, S., Qi, M. & Shu, R. Mol. Med. Rep. 12, 5239–5245 (2015).
Hasturk, H. et al. Arterioscler. Thromb. Vasc. Biol. 35, 1123–1133 (2015).
Acknowledgements
We thank the workshop speakers for participating and for providing insight in addressing the challenges associated with biomarker identification and leveraging and developing imaging and sensing technologies, as well as strategies for data integration during chronic inflammatory conditions, and for their time and input in reviewing the manuscript. Workshop organizing committee: Natalie Abram, Danielle Carrick, Paige Green, Richard Mazurchuk, Sudhir Srivastava, Piotr Grodzinski, Grace Shen, Julia Berzhanskaya, Antonello Punturieri, Andrei Kindzelski, Barbara Radziszewska, Felipe Sierra, Ronald Kohanski, Miroslaw Mackiewicz, Francesca Macchiarini, Mercy PrabhuDas, Merriline Vedamony, Preethi Chander, Michelle Hamlet and Johanna Dwyer.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Liu, C., Abrams, N., Carrick, D. et al. Biomarkers of chronic inflammation in disease development and prevention: challenges and opportunities. Nat Immunol 18, 1175–1180 (2017). https://doi.org/10.1038/ni.3828
Published:
Issue Date:
DOI: https://doi.org/10.1038/ni.3828
- Springer Nature America, Inc.
This article is cited by
-
Comprehensive Analysis of Computational Methods for Predicting Anti-inflammatory Peptides
Archives of Computational Methods in Engineering (2024)
-
The metabolites of Piper sarmentosum and their biological properties: a recent update
Phytochemistry Reviews (2024)
-
Evaluation of COX-2 production, anticancer efficacy against MCF-7 cell lines, and antioxidant activity of Garcinia conicarpa, a novel endemic species of the Western Ghats
Vegetos (2023)
-
Phase angle and cellular health: inflammation and oxidative damage
Reviews in Endocrine and Metabolic Disorders (2023)
-
Spatially resolved in vivo imaging of inflammation-associated mRNA via enzymatic fluorescence amplification in a molecular beacon
Nature Biomedical Engineering (2022)