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To B-1 or not to B-1

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The transcription factor Bhlhe41 determines the survival and repertoire of B-1a cells.

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Figure 1: Multiple mechanisms ensure the generation of B cells that produce natural self-reactive antibodies.

Debbie Maizels/ Springer Nature

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Authors and Affiliations

  1. Henry H. Wortis is with the Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, Massachusetts, USA.,

    Henry H Wortis

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  1. Henry H Wortis
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Correspondence to Henry H Wortis.

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Wortis, H. To B-1 or not to B-1. Nat Immunol 18, 365–366 (2017). https://doi.org/10.1038/ni.3715

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