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How MAIT cells get their start

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By taking advantage of an MR1 tetramer to accurately detect mucosal-associated invariant T (MAIT) cells in both mice and humans, researchers defined the thymic development of MAIT cells.

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Figure 1: Parallels and differences in development between MAIT cells and iNKT cells.

Kim Caesar/Nature Publishing Group

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Authors and Affiliations

  1. Haiguang Wang and Kristin A. Hogquist are at the Department of Laboratory Medicine & Pathology and the Center for Immunology, University of Minnesota, Minneapolis, Minnesota, USA.,

    Haiguang Wang & Kristin A Hogquist

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  1. Haiguang Wang
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  2. Kristin A Hogquist
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Correspondence to Kristin A Hogquist.

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The authors declare no competing financial interests.

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Wang, H., Hogquist, K. How MAIT cells get their start. Nat Immunol 17, 1238–1240 (2016). https://doi.org/10.1038/ni.3584

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