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Immunity without innate lymphoid cells

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A cohort of immunodeficient children lead near-normal lives after bone marrow transplantation, despite a profound deficiency of innate lymphoid cells (ILCs).

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Figure 1: Immune-cell reconstitution in children with SCID due to mutations in IL2RG or JAK3 after hematopoietic stem cell (HSC) transplantation.

Kim Caesar/ Nature Publishing Group

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Authors and Affiliations

  1. Robert Weinkove is at the Malaghan Institute of Medical Research; and the Department of Pathology and Molecular Medicine, University of Otago, Wellington, New Zealand.,

    Robert Weinkove

  2. the Wellington Blood & Cancer Centre, Capital & Coast District Health Board,

    Robert Weinkove

  3. Kara Filbey and Graham Le Gros are at the Malaghan Institute of Medical Research, Wellington, New Zealand.,

    Kara Filbey & Graham Le Gros

Authors
  1. Robert Weinkove
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  2. Kara Filbey
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  3. Graham Le Gros
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Corresponding author

Correspondence to Graham Le Gros.

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The authors declare no competing financial interests.

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Weinkove, R., Filbey, K. & Le Gros, G. Immunity without innate lymphoid cells. Nat Immunol 17, 1237–1238 (2016). https://doi.org/10.1038/ni.3567

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