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Broad and strong: the ultimate antibody to dengue virus

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The identification of a new class of cross-reactive monoclonal antibodies that strongly neutralize all four serotypes of dengue virus has important implications for vaccine design as well as for the evaluation of vaccines and of natural infection with dengue virus.

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Figure 1: Potently neutralizing human DENV-specific antibodies after primary and secondary DENV infection.

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Authors and Affiliations

  1. Josefina Coloma and Eva Harris are in the Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, California, USA.,

    Josefina Coloma & Eva Harris

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  1. Josefina Coloma
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  2. Eva Harris
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Correspondence to Eva Harris.

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The authors declare no competing financial interests.

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Coloma, J., Harris, E. Broad and strong: the ultimate antibody to dengue virus. Nat Immunol 16, 135–137 (2015). https://doi.org/10.1038/ni.3081

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